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Can your antidepressant stop working? However, in some people, a particular antidepressant may simply stop working over time. Doctors don't fully understand what causes the so-called "poop-out" effect or antidepressant tolerance — known as tachyphylaxis — or why it occurs in some people and not in others.
What happens if I miss my antidepressants? If you do miss 1 of your doses, take it as soon as you remember, unless it's almost time to take your next dose. In this case, you should just skip the missed dose. Taking a double dose is unlikely to be harmful, but you should only do so if advised by a medical professional.
How long does it take for sertraline to work? Antidepressants like sertraline can start to work on depression within the first two weeks of treatment, and the improvement continues over the following few weeks. It may take four weeks or longer for you to get the full effect. For anxiety, antidepressants like sertraline can take slightly longer to work.
What painkillers can I take with fluoxetine? It is fine to take painkillers such as paracetamol, co-codamol with fluoxetine. anti-inflammatory painkillers (NSAIDs) such as diclofenac, ibuprofen, diclofenac and naproxen should be used with caution if you are taking fluoxetine, as there is an increased risk of bleeding the gut if taken together.
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